CiteScore: 1.9     h-index: 21

Document Type : Original Research Article

Authors

Department of Chemistry, University of North Bengal, District Darjeeling, West Bengal, India

Abstract

A green and facile methodology for the synthesis of nitrile has been established from the corresponding aldehydes and hydroxylamine hydrochloride on silica-gel in hot condition. The protocol is equally effective for aliphatic as well as aromatic aldehydes, and has wide range of functional group tolerance. In addition, this methodology is solvent-free, inexpensive, environmental friendly and involves simple work-up process.

Graphical Abstract

One-pot route to nitriles from aldehyde and hydroxylamine hydrochloride on silica-gel

Keywords

Main Subjects

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