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Document Type : Original Research Article


1 Department of Chemistry, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran

2 Department of Chemistry, Tarbiat Modares University, P.O. BOX, 14115-175, Tehran, Iran


The combination of isatins, active methylene reagents and 4-phenylurazole/ phthalhydrazide in the presence of ionic liquid ([BMIm]Cl) as a solvent catalyst was found to be a suitable and efficient method for the synthesis of the biologically important spirooxindoles. The features of this procedure were characterized by one-pot procedure, reasonable reaction times, fairly high yields, and simple isolation procedures. The ionic liquid can be easily separated and reused for several times.

Graphical Abstract

An efficient approach to the synthesis of some novel heterocycles related to indoline moiety using [BMIm]Cl catalysis


Main Subjects

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How to cite this manuscript: Leila Youseftabar-Miri, Hamide Hosseinjani-Pirdehi. An efficient approach to the synthesis of some novel heterocycles related to indoline moiety using [BMIm]Cl catalysis. Asian Journal of Green Chemistry, 2017, 2(2), 56-57. DOI: 10.22631/ajgc.2017.95721.1017