Asian Journal of Green Chemistry
3.8(Q2)
CiteScore
27
h-index

Exploration of Antioxidant and Anti-inflammatory Activities in Various Parts of Thunbergia fragrans

Articles in Press

Document Type : Original Research Article

Authors

Kasinath Baratam
Boddu Veeraswami

Department of Chemistry, GITAM School of Science, GITAM Deemed to Be University, Visakhapatnam–530045, Andhra Pradesh, India

10.48309/ajgc.2026.559072.1875
Abstract
Oxidation and inflammation are key contributors to chronic diseases such as cancer, cardiovascular disorders, and neurodegeneration. Reactive oxygen species (ROS) cause cellular damage, while chronic inflammation can worsen health outcomes. Antioxidants, though protective against ROS, may have adverse effects when excessively supplemented. This research highlights the importance of natural sources for the extraction of Thunbergia fragrans, a medicinal plant, was studied for its antioxidant and anti-inflammatory properties using 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging and membrane stabilization assays. Methanol extracts of both leaf and stem showed strong bioactivity (51.63% and 60.32%, respectively), with the leaf extracts nearing the efficacy of diclofenac, the standard anti-inflammatory drug. In contrast, aqueous extracts showed lower activity (79.26), underscoring the role of methanol (97.6) in extracting bioactive compounds. These findings suggest that Thunbergia fragrans is a promising source of natural therapeutic agents. Further research is needed to isolate and characterize the specific compounds responsible for the observed effects.

Graphical Abstract

Exploration of Antioxidant and Anti-inflammatory Activities in Various Parts of Thunbergia fragrans

Keywords

Thunbergia fragrans
Antioxidant
Anti-inflammatory
ROS
DPPH

Subjects

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Asian Journal of Green Chemistry

Articles in Press, Accepted Manuscript
Available Online from 12 February 2026

  • Receive Date 25 November 2025
  • Revise Date 03 January 2026
  • Accept Date 07 February 2026

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