TY - JOUR ID - 77204 TI - Facile ionic liquid-mediated, multi component synthesis of dihydro-1H-furo[2,3-c]pyrazoles JO - Asian Journal of Green Chemistry JA - AJGC LA - en SN - 2588-5839 AU - Tangeti, Venkata Swamy AD - Dr. S.R.K. Government Arts College (Pondicherry University), Yanam, U.T of Puducherry, India Y1 - 2019 PY - 2019 VL - 3 IS - 3 SP - 306 EP - 321 KW - Ionic liquid Multi component reaction (MCR) Dihydrofuro[1 KW - 2b]pyrazole Green synthesis DO - 10.22034/ajgc.2018.142927.1090 N2 - A facile, convenient, efficient, and high-yielding diastereoselective synthesis of a novel fused dihydro-1H-furo[2,3-c]pyrazole by a one-pot four-component reaction of β-keto ester, hydrazine, aromatic aldehyde and pyridinium salt in the presence of [bmIm]OH ionic liquid medium provided with excellent yields. Three new bonds (two C‒C and one C‒O), and two stereo centres are generated in a single operation. Low cost, short reaction time, excellent yield, operational simplicity, and more importantly the purification of the compounds by a non-chromatographic method make this process very significant for academic research and practical applications. UR - https://www.ajgreenchem.com/article_77204.html L1 - https://www.ajgreenchem.com/article_77204_6d4163702ef4f6bc820bd53bc846b470.pdf ER -