@article { author = {Tangeti, Venkata Swamy}, title = {Facile ionic liquid-mediated, multi component synthesis of dihydro-1H-furo[2,3-c]pyrazoles}, journal = {Asian Journal of Green Chemistry}, volume = {3}, number = {3}, pages = {306-321}, year = {2019}, publisher = {Sami Publishing Company}, issn = {2588-5839}, eissn = {2588-4328}, doi = {10.22034/ajgc.2018.142927.1090}, abstract = {A facile, convenient, efficient, and high-yielding diastereoselective synthesis of a novel fused dihydro-1H-furo[2,3-c]pyrazole by a one-pot four-component reaction of β-keto ester, hydrazine, aromatic aldehyde and pyridinium salt in the presence of [bmIm]OH ionic liquid medium provided with excellent yields. Three new bonds (two C‒C and one C‒O), and two stereo centres are generated in a single operation. Low cost, short reaction time, excellent yield, operational simplicity, and more importantly the purification of the compounds by a non-chromatographic method make this process very significant for academic research and practical applications.}, keywords = {Ionic liquid Multi component reaction (MCR) Dihydrofuro[1,2b]pyrazole Green synthesis}, url = {https://www.ajgreenchem.com/article_77204.html}, eprint = {https://www.ajgreenchem.com/article_77204_6d4163702ef4f6bc820bd53bc846b470.pdf} }