Document Type: Original Research Article
Author
Department of Chemistry, College of Science, University of Mosul, Mosul, Iraq
Abstract
New series of hippuric hydrazones 4–8 were synthesized starting from treating the corresponding acid with ethanolic HCl forming the corresponding ester 2. The formed ester was then converted to ethyl hippurate 3 by treating the ester with hydrazine hydrate. Under solvent-free conditions the formed ethyl hippurate was allowed to irradiate with various substituted aromatic aldehydes forming new series of hippuric hydrazones 4–8. The aim of this work is to develop clean synthetic route for hippuric hydrazones which is economically and environmentally desirable. The structure of the synthesized compounds was confirmed based on their analytical spectral NMR, mass, IR and CHN analysis data.
Graphical Abstract
 "Green synthesis of new hippuric hydrazones")
Keywords
Main Subjects
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