CiteScore: 1.9     h-index: 21

Document Type : Original Research Article

Authors

1 Department of Chemistry, Payame Noor University, PO Box 19395-4697, Tehran, Iran

2 Laboratory of Advanced Catalysis for Sustainability, School of Chemistry, The University of Sydney, Sydney 2006, Australia

Abstract

One-pot synthesis of Hantzsch 1,4-dihydropyridines (1,4-DHP) under solvent-free conditions catalyzed by HKUST-1 metal-organic frameworks are reported here. This method provides 1,4-dihydropyridines in good to excellent yields with little catalyst loading. The present methodology offers several advantages, including ease of the preparation and handling of the catalyst, simple and easy work-up, short reaction times, high yields of the products and recyclability of the catalyst.
One-pot synthesis of Hantzsch 1,4-dihydropyridines (1,4-DHP) under solvent-free conditions catalyzed by HKUST-1 metal-organic frameworks are reported here. This method provides 1,4-dihydropyridines in good to excellent yields with little catalyst loading. The present methodology offers several advantages, including ease of the preparation and handling of the catalyst, simple and easy work-up, short reaction times, high yields of the products and recyclability of the catalyst.

Graphical Abstract

HKUST-1 as an efficient and reusable heterogeneous catalyst for synthesis of 1,4-dihydropyridine at room temperature

Keywords

Main Subjects

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