Document Type: Original Research Article

Author

Dr. S.R.K. Government Arts College (Pondicherry University), Yanam, U.T of Puducherry, India

Abstract

A facile, convenient, efficient, and high-yielding diastereoselective synthesis of a novel fused dihydro-1H-furo[2,3-c]pyrazole by a one-pot four-component reaction of β-keto ester, hydrazine, aromatic aldehyde and pyridinium salt in the presence of [bmIm]OH ionic liquid medium provided with excellent yields. Three new bonds (two C‒C and one C‒O), and two stereo centres are generated in a single operation. Low cost, short reaction time, excellent yield, operational simplicity, and more importantly the purification of the compounds by a non-chromatographic method make this process very significant for academic research and practical applications.

Graphical Abstract

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Main Subjects

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How to cite this manuscript: Venkata Swamy Tangeti. Facile ionic liquid-mediated, multi component synthesis of dihydro-1H-furo[2,3-c]pyrazoles.Asian Journal of Green Chemistry, 3(3) 2019, 306-321. DOI: 10.22034/ajgc.2018.142927.1090