Document Type: Original Research Article

Authors

1 Department of Chemistry, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran

2 Department of Chemistry, Tarbiat Modares University, P.O. BOX, 14115-175, Tehran, Iran

Abstract

The combination of isatins, active methylene reagents and 4-phenylurazole/ phthalhydrazide in the presence of ionic liquid ([BMIm]Cl) as a solvent catalyst was found to be a suitable and efficient method for the synthesis of the biologically important spirooxindoles. The features of this procedure were characterized by one-pot procedure, reasonable reaction times, fairly high yields, and simple isolation procedures. The ionic liquid can be easily separated and reused for several times.

Graphical Abstract

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How to cite this manuscript: Leila Youseftabar-Miri, Hamide Hosseinjani-Pirdehi. An efficient approach to the synthesis of some novel heterocycles related to indoline moiety using [BMIm]Cl catalysis. Asian Journal of Green Chemistry, 2017, 2(2), 56-57. DOI: 10.22631/ajgc.2017.95721.1017